FiteBac® dental video library
FiteBac, manufacturer of patented antimicrobial compounds and additives for dentistryand medicine, announces partnership with RDAbbott to provide non-leaching, durableand persistent bactericidal, fungicidal, and virucidal protection in synthetic and siliconerubbers....
FiteBac Technology and Siltech team up to manufacture novel antimicrobial silsesquioxanes with advanced properties.
Summary: After the successful launch of multiple FDA-cleared antimicrobial dental devices, FiteBac partners with Siltech, an international corporation specializing in innovative silicone products, to develop novel materials imbued with FiteBac’s broad antimicrobial...
U.S.-Based FiteBac Presents in Germany for First Time at International Dental Show, IDS2021, to Feature New Antimicrobial Additives for Dental Restorative MaterialsSummary: FiteBac will be a new, featured presenter at the world’s largest dental conference, IDS 2021,...
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Quaternary Ammonium Methacryloxy Silicate-containing Acrylic Resin
One of the major challenges in orthodontic treatment is long-term stability. Because removable retainers are worn for at least 1 year, bacteria and fungi may accumulate on the retainers in the form of multi-species plaque biofilms. This may result in increased incidence of proximal dental caries or oral candida infection. Thus, incorporation of antimicrobial activity in orthodontic acrylic resin to achieve plaque biofilm reduction is highly desirable. An antimicrobial and antifungal quaternary ammonium methacryloxy silicate (QAMS) molecule has been synthesized by sol-gel reaction and incorporated into orthodontic acrylic resin.
The QAMS-copolymerized acrylic resin demonstrated contact-killing properties against single-species biofilms in previous in vitro studies and has received US FDA 510(K) clearance for marketing.
The objective of the present randomized clinical trial is to determine the in vivo antimicrobial efficacy of the QAMS-containing orthodontic acrylic by using removable retainers that are worn by recruited subjects to create 48-hour multi-species plaque biofilms. The null hypothesis tested is that there is no difference in the antimicrobial activities between QAMS-free and QAMS-containing orthodontic acrylic resin on oral biofilms grown in vivo in human subjects.